[CowboyRam]

I have heard that cattle get a resistance to Noromectin, and therefore one should switch out every few years with Ivomec pour-on. Have any of you guys heard this? Opinions?

 

[Rrueda]

Yes. In fact it is not cattle but parasites that end up being resistant to whatever you use. Better use a different molecule every time.

If you are running a cow calf operation I would strongly suggest selection against that trait.

 

[CowboyRam]

Yes. In fact it is not cattle but parasites that end up being resistant to whatever you use. Better use a different molecule every time.

If you are running a cow calf operation I would strongly suggest selection against that trait.

Last year I did use Noromectin, and yes I should of said parasites. I guess I should change to Ivomec for this year. It just cost more.

 

[Edd in KY]

Isn't the main ingredient the same in both? If so it will not change the resistance problem on your property.

 

[CowboyRam]

Isn't the main ingredient the same in both? If so it will not change the resistance problem on your property.

That I don't know. I will have to take a look at that.

 

[Trillium Farm]

That I don't know. I will have to take a look at that.

Anything ending with .....mectin is the same ingredient.

 

[Hayjosh]

They're both ivermectin. You're changing who you are giving your money to, but not the drug. You need to change the active ingredient, and more frequently than every few years.

 

[Rrueda]

Anything ending with .....mectin is the same ingredient.

Not really. Ivermectin, doramectin and noramectin are different molecules.

 

[Markpnw]

Not really. Ivermectin, doramectin and noramectin are different molecules.

They are the same active ingredient. Doramectin is a derivative of ivermectin which means it’s the same stuff. If the parasites are resistant to ivermectin they’ll be resistant to doramectin and noramectin. Has anybody used amitraz to treat cattle?

 

[Rrueda]

If the parasites are resistant to ivermectin they’ll be resistant to doramectin and noramectin.

As far as I know, there is no scientific research available to back up that claim. Moxidectin is yet another option for the OP, it works for internal and external parasites and has less environmental impact. If money is not an obstacle, get Eprinomectin which is an extended release molecule and lasts for 150 days.

As for Amitraz, it works only for external parasites.

 

[Markpnw]

As far as I know, there is no scientific research available to back up that claim. Moxidectin is yet another option for the OP, it works for internal and external parasites and has less environmental impact. If money is not an obstacle, get Eprinomectin which is an extended release molecule and lasts for 150 days.

As for Amitraz, it works only for external parasites.

There really isn’t a lot of research papers in general about agricultural parasites. I’ve done plenty of research and if a certain parasite is resistant to a chemical ivermectin anything else that is a derivative will or is already resistant. If the parasite became resistant to ivermectin how is doramectin going to be better when it’s a derivative of the same thing. Slow release stuff is even worse because the parasite has more time to adapt to it.

 

[Hayjosh]

There really isn’t a lot of research papers in general about agricultural parasites. I’ve done plenty of research and if a certain parasite is resistant to a chemical ivermectin anything else that is a derivative will or is already resistant. If the parasite became resistant to ivermectin how is doramectin going to be better when it’s a derivative of the same thing. Slow release stuff is even worse because the parasite has more time to adapt to it.

I agree in general, however there is a trove of research available. Parasiticides are a very big industry $$.

 

[jr in va]

I've heard you really need to take fecal samples for a vet to check to see what worms you need to target and use what works best. Also stay with an Ivomec type product until it shows resistance then switch to one of the white drench dewormers. Makes sense.

 

[Trillium Farm]

I've heard you really need to take fecal samples for a vet to check to see what worms you need to target and use what works best. Also stay with an Ivomec type product until it shows resistance then switch to one of the white drench dewormers. Makes sense.

I was always told to rotate type as once resistance is established it cannot be undone!
Rotation is supposed to stop resistance, for rotation is meant every use with a different type at the very least in alternation, but if not possible not more than 2 or 3 in sequence of the same type.

 

[Markpnw]

I was always told to rotate type as once resistance is established it cannot be undone!
Rotation is supposed to stop resistance, for rotation is meant every use with a different type at the very least in alternation, but if not possible not more than 2 or 3 in sequence of the same type.

Rotation is the best bet.

 

[jr in va]

I've also read that you should use one type of dewormer until it isn't effective then switch. A simple rotation may cause resistance to both types. ?

 

[Ray 54]

I've also read that you should use one type of dewormer until it isn't effective then switch. A simple rotation may cause resistance to both types. ?

I cannot say I have asked about official about the wormer, but situations like with weeds and fungicides killing mold and mildew I have sat through many grower meeting with chemical company , and university professors all saying change every time . With luck using different chemistry it kills those that had immunity to what you used last time. So it was change fast and often. So I would think this is the same.

 

[Trillium Farm]

I've also read that you should use one type of dewormer until it isn't effective then switch. A simple rotation may cause resistance to both types. ?

NO, one ought to use a different "KIND" not just a different name EVERY time.
If you wait till one type is no longer effective, the parasite have developed a defense against it and all future generations will be resistant, by changing type every-time the parasite does not have the time to develop and adapt.

 

[Hayjosh]

I've also read that you should use one type of dewormer until it isn't effective then switch. A simple rotation may cause resistance to both types. ?

Why on earth would you establish resistance and THEN switch? You'll never be able to use that parasiticide again.

 

[Trillium Farm]

Why on earth would you establish resistance and THEN switch? You'll never be able to use that parasiticide again.

EXACTLY !!!!